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Proc Natl Acad Sci 100:94409445 Su YW, Chen X, Jiang ZZ, Wang T, Wang C, Zhang Y, Wen J, Xue M, Zhu D, Su YJ, Xing TY, Zhang CY, Zhang LY (2012) A panel of serum microRNAs as specific biomarkers for diagnosis of compound- and herb-induced liver injury in rats

So, it is likely that OS can be triggered by following an increase in the production of O2 - and NO in MNs as well as in the central glia, starting from the presymptomatic phase of ALS

Cells exposed to varying percentage of oxygen showed increased reactive oxygen species and cell death